Estudio del Valor predictivo del ultrasonido como único tamizaje de cro - mosomopatías en gestantes dentro del primer trimestre gestacional en el Centro Imagenológico Ecosalud Guayaquil durante el período 2019-2021
The objective of this study was to establish the predictive value of the measurement of nuchal translucency, nasal bone and ductus venosus in the ultrasound of first trimester pregnant women as an ultrasonographic marker of aneuploidies. A universe of 341 pregnant women and 345 screenings (4 twin pr...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | Spanish |
| Published: |
2023
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| Subjects: | |
| Online Access: | https://dialnet.unirioja.es/servlet/oaiart?codigo=9003049 |
| Source: | RECIMUNDO: Revista Científica de la Investigación y el Conocimiento, ISSN 2588-073X, Vol. 7, Nº. 1, 2023, pags. 716-726 |
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| Summary: |
The objective of this study was to establish the predictive value of the measurement of nuchal translucency, nasal bone and ductus venosus in the ultrasound of first trimester pregnant women as an ultrasonographic marker of aneuploidies. A universe of 341 pregnant women and 345 screenings (4 twin pregnant women) were studied from 09-1-2019 to 08-31-2021 at the Ecosalud-Ecuador Imaging Center, the Fetal Medicine Foundation Astraia 2.8.1 program was used. for data processing and risk assessment. The general behavior of ultrasonographic markers considering maternal age was studied, the effectiveness of nuchal translucency, ductus and nasal bone in the detection of products with chromosomal disease was determined by studying the cases at the end of gestation. It was an applied research of an observational, documentary, analytical, retrospective cross-sectional type with a non-experimental design with a quantitative approach, diagnostic test studies were carried out with diagnostic calculation indices. The results were 6 fetuses with increased ultrasonographic
markers confirmed with karyotype 2 chromosomopathies[21(Down) and 13(Patau)]. The sensitivity was 100% and the specificity 99.71%. The positive predictive values were 66.67% and the negative ones were 100%. No false negatives were obtained and the false positive rate was biased as aneuploidy could not be confirmed in 2 abortions that had to be excluded. In conclusion, the high specificity and negative predictive values reaffirm these markers as very good at detecting the risk of chromosomal disease, especially for trisomy 21, 18 (Edwards), 13 which leads to a minimal indication of invasive obstetric procedures and an increase in the detection of fetal defects being considered an excellent system to be incorporated in primary care health centers. |
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